Images

Whole exon capture sequencing. The image show how sequenced sequences are piled up around the exons of Dgcr8 gene in a child (top) and his/her parents (middle and bottom). Courtesy of Bin Xu.
Copy number mutation analysis of Affymetrix GeneChip data indicates a deletion (blue region) in one of the patient samples. Each column represents a sample. Courtesy of Bin Xu.
microRNA profiling analysis using two-color microarrays to compared microRNA expression between mutant and wild type mice. Courtesy of Bin Xu.
Hippocampus from Thy-1-GFP reporter mice counter-stained for VGLUT1. Courtesy of Jun Mukai.
BrdU labeled cells in P0 mouse cortex. Green signal: BrdU, Red signal: Tbr-1, Blue signal: CTIP2. Courtesy of Jun Mukai.
GFP retrovirus expression in 4-week old granule cells at the dentate gyrus. Courtesy of Heather McKellar and Mirna Kvajo.
  Electron micrograph of mossy fiber terminal (MFT) in the CA3 region of the hippocampus. MFTs form synaptic densities with the spines (S) and dendrites (D) of CA3 pyramidal cells. Courtesy of Heather McKellar and Mirna Kvajo.
An array of extracellular voltage traces from a slice of mouse hippocampus in which gamma oscillations were induced with kainic acid. Courtesy of Timothy Spellman and Liam Drew.
Waveforms of extracellularly recorded (stereotrode) action potentials from a mouse cortex in vivo, clustered for isolation of individual cells. Courtesy of Timothy Spellman.
Immunocytochemical staining of mouse induced pluripotent stem cells with the nuclear marker Oct4. Courtesy of Florence Chaverneff.
Flourescent in situ hybridization (FISH) using BAC probes located both within a deleted region (red), as well as outside of a deleted region (green), reveals a heterozygous deletion on mouse chromosome 16 (the region syntenic to that of human chromosome 22q11). Courtesy of Kim Stark.
Manhattan plot from a schizophrenia genome-wide association study. Courtesy of Laura Rodriguez Murillo.
Linkage disequilibrium structure on a region of the human genome, as obtained from HapMap. Red squares represent areas of high LD. Courtesy of Laura Rodriguez Murillo.